Get dosing information on FARXIGA® (dapagliflozin), for the treatment of type 2 diabetes mellitus. Visit for more. Forxiga is indicated in adults aged 18 years and older with type 2 diabetes Forxiga can be taken orally once daily at any time of day with or without food. FORXIGA® is a registered trademark of AstraZeneca AB, used under . Monotherapy: FORXIGA (dapagliflozin) is indicated for use as an.
|Published (Last):||21 December 2016|
|PDF File Size:||6.37 Mb|
|ePub File Size:||13.52 Mb|
|Price:||Free* [*Free Regsitration Required]|
EPAR summary for the public: Not available for government-insured patients. Monitor for signs and symptoms. If suspected, farxiba promptly and do not restart if confirmed.
Seek medical attention immediately if you have fever or you are feeling very weak, tired or uncomfortable and you also develop any pain or tenderness, swelling, or redness of the skin in the genitals and areas around them Vaginal yeast infections in women who take FARXIGA.
Use with caution in patients with a history of bladder cancer Macrovascular Outcomes: FARXIGA is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.
The secret to managing type 2 diabetes is to take small fraxiga and your first step is to sign up now. Evaluate for signs and symptoms of UTIs farrxiga treat promptly. Not available for government-insured patients. This infection has happened in women and men and may lead to hospitalization, surgeries and death.
You may report side effects related to AstraZeneca products by clicking here. Rare but serious infections that cause severe tissue damage under the skin of the genitals and areas around them have happened with FARXIGA.
A subset of patients experienced a recurrence of symptoms when restarting the same drug or a different DPP-4 inhibitor.
You may report side effects related to AstraZeneca products by clicking here. Check out the Patient Dialogue section for thought starters on guiding initial conversations and answering patient questions. There have been postmarketing reports of acute pancreatitis in patients taking saxagliptin and in the SAVOR cardiovascular outcomes trial.
Use with caution in patients with a history of bladder cancer Severe and Disabling Arthralgia has been reported in patients taking DPP-4 inhibitors. Accessed September 28, Dapagliflozin, metformin XR, or both: Int J Clin Pract.
Type 2 Diabetes Treatment | QTERN® (dapagliflozin and saxagliptin) – For HCPs
Accessed August 27, Elderly patients and patients with impaired renal function may be more susceptible to these changes. The pill that starts with. Symptoms of a serious allergic reaction may include skin rash, raised red patches on your skin hivesswelling of the face, lips, tongue, and throat that may cause difficulty in breathing or swallowing.
Assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis regardless of blood glucose level.
Patients experienced relief of symptoms upon discontinuation. Not recommended in patients with severe renal impairment or end-stage renal disease. Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy DURATION Advise females of potential risk to farxiag fetus especially during the second and third trimesters.
Ketoacidosis has been reported in patients with farxkga 1 and type 2 diabetes receiving dapagliflozin.
Monitor and treat appropriately. J Clin Endocrinol Metab.
In the SAVOR cardiovascular outcomes trial, more patients treated with saxagliptin were hospitalized for heart failure compared to placebo.
AstraZeneca Pharmaceuticals LP; Take the Next Step. Use in Specific Populations Pregnancy: Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm— executive summary.
Onset of these reactions occurred within the first 3 months after initiation of treatment with saxagliptin, with some reports occurring after the first dose. Tell your doctor if you have any signs or symptoms of UTI including a burning feeling when passing urine, a need to urinate often, the need to urinate right away, pain in the lower part of your stomach pelvisor blood in the urine with or without fever, back pain, nausea, or vomiting Low blood sugar hypoglycemia can occur if you take FARXIGA with another medicine that can cause low blood sugar, such as sulfonylureas or insulin.
Consider other antidiabetic therapies in patients with a history of pancreatitis Hypoglycemia Risk of hypoglycemia is increased when exenatide is coadministered with insulin or insulin secretagogues.
Centers for Disease Control and Prevention. If acute kidney injury occurs, discontinue and promptly treat.
FARXIGA helps lower A1C by up to 1.2% points.
Elderly patients and patients with impaired renal function may be more susceptible to these changes. Symptoms of low blood sugar include shaking, sweating, fast heartbeat, dizziness, hunger, headache, and irritability. FARXIGA should not be used to treat people with type 1 diabetes or diabetic ketoacidosis increased ketones in your blood or urine. Effect of dapagliflozin in patients with type 2 diabetes who have inadequate glycaemic control with metformin: AstraZeneca Pharmaceuticals LP; After initiation, observe patients carefully for symptoms of pancreatitis.
Consider temporarily discontinuing in settings of reduced oral intake or fluid losses. Consider discontinuing drug if appropriate Bullous Pemphigoid: Tell your healthcare provider right away if you have blood or a red color in your urine or pain while you urinate The most common side effects of FARXIGA include yeast infections of the vagina or penis, and changes in urination, including urgent need to urinate more often, in larger amounts, or at night.
Talk to your doctor right away if you reduce the amount you eat or drink, or if you lose liquids; for example, from vomiting, diarrhea, or excessive heat exposure Serious urinary tract infections UTIsome that lead to hospitalization, occurred in people taking FARXIGA. Dapagliflozin causes intravascular volume contraction and symptomatic hypotension can occur.
Farsiga Engl J Med. The time to onset of symptoms following initiation of drug therapy varied from one day to fafxiga. Assess and correct volume status before initiating FARXIGA in patients with impaired renal function, elderly patients, or patients on loop diuretics.