The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. The stability of. PDF | Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic.

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Medical Applications of Controlled Release. The drug release from all the emulgels was found to follow diffusion-controlled mechanism.

The Pharmaceutical Press; Az J Pharm Sci.

Optimization of chlorphenesin emulgel formulation

Transdermal controlled release systems. As a general conclusion, it was suggested that the CHL emulgel formulation prepared with HPMC with the oil phase concentration in its low level and emulsifying agent concentration in its high level was the formula of choice since it showed the highest drug release and antifungal activity.

Development of a thermoreversible gel for controlled-release ocular delivery of diclofenac sodium. Lea and Febiger; The Complete Drug Reference. Rheological studies revealed that the CHL emulgels exhibited a shear-thinning behavior with thixotropy.


Bioavailability of salbutamol sulphate from different suppository formulations. Formulation and evaluation of topical preparations containing phenol and local vesicants. This article has been cited by other articles in PMC. The Theory and Practice of Industrial Pharmacy. Formulation and stability of chloramphenicol gel and emulgel. Please review our privacy policy.

Optimization of chlorphenesin emulgel formulation

Received Dec 31; Accepted May Marcel Dekker Inc; All the prepared emulgels showed acceptable physical properties concerning color, homogeneity, consistency, spreadability, and pH value. Support Center Emulel Center. Blackwell Scientific Publications; emullgel Egypt J Pharm Sci. This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: Swarbrick J, Boylan JC, editors.

Published online Sep 1. It was found that the emulsifying agent concentration had the most pronounced effect on the drug release from the emulgels followed by the oil phase concentration and finally the type of the gelling agent.

The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug release from the prepared emulgels was investigated using a 2 3 factorial design.


A study of shear and compression deformations on hydrophilic gels of tretinoin. Commercially available CHL topical powder was used for comparison. Preparation of an emulgel for treatment rormulation aphthous ulcer on the basis of carbomers. Abstract This study was conducted to develop an emulgel formulation of chlorphenesin CHL using 2 types of gelling agents: The prepared emulgels were evaluated for their physical appearance, rheological emuogel, drug release, antifungal activity, and stability.

Stability studies showed that the physical appearance, rheological formylation, drug release, and antifungal activity in all the prepared emulgels remained unchanged upon storage for 3 months.

Analysis of data on the medicament release from ointments. They also exhibited higher drug release and antifungal activity than the CHL powder. National Center for Biotechnology InformationU. Author information Article notes Copyright and License information Disclaimer.

Encyclopedia of Pharmaceutical Technology.