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The hospital mortalities were 1. The statistician was blinded to the study. The patients with CAP might be triaged more appropriately according to simplified minor criteria, and most accurately by using the modified version.
We found that the 4 noncontributory or infrequent variables leukopenia, hypothermia, hypotension, and thrombocytopenia could be removed and that the deletion improved PPV and AUC for the prediction of mortality in the 2 cohorts.
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With relatively important differences in the presentation, the prospective validation cohort included more severely ill patients.
The sensitivities, specificities, positive predictive values PPVsnegative predictive values, and Youden indices were also calculated. MJ was in charge of statistical analysis. A total of patients were enrolled consecutively, and 15 cases were excluded from the retrospective cohort due to exclusion criteria. Hosp Pract ; Clin Infect Dis ; 44 Suppl 2: The simplification and modification were tested against the prospective 2 center validation cohort.
Hence, further studies are warranted. Salih et al 7 recently discovered that a simplified score excluding 3 variables leukopenia, hypothermia, and thrombocytopenia was performed similarly for the prediction of mortality and ICU admission.
Ethical approval from the regulation committee Ethical Committee of Shenzhen was granted for the study protocol. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock.
Modified IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia Best Predicted Mortality
This article has been corrected. CURB scoring system performs well at identifying patients with pneumonia who have a low risk of death. Future prospective clinical multicenter studies should also be performed to assess the generalizability.
What we suggested might constitute 2 more pragmatic rules, which were more suitable for clinic and emergency department, to predict mortality from CAP.
This study has 3 main limitations.
Chi-square test and univariate logistic regression were employed. Accuracy of ICU admission prediction is pivotal to improve patient management. Value of severity scales in predicting mortality from community-acquired pneumonia systematic review and meta-analysis.
Inclusion of clasificacjon variables might incur higher false positive rate i. Athe planned science and technology project of Shenzhen municipality in No. Intern Med ; The highest accuracy of the modified version for predicting mortality in the retrospective cohort was illustrated by the highest area under the receiver operating characteristic curve of 0. If the population of patients to which the score is being applied is significantly different from the original derivation it may be necessary to perform local recalibration of the score.
Clin Infect Dis ; Causes and factors associated with early failure in hospitalized patients with community-acquired pneumonia.
J Crit Care ; Comparison of clinical characteristics and performance of pneumonia severity score and CURB among younger adults, elderly and very old subjects.
Severity assessment tools for predicting mortality in hospitalised patients with community-acquired tubercuoosis. They clasificacin help us make more accurate clinical decisions about where these patients should be tuebrculosis at ICU vs non-ICUand need for advance care.
Index of /library
The findings might have been more robust with a greater number of patients met the criteria. Severe community-acquired pneumonia assessment of microbial aetiology as mortality factor.
Contributed by H-YL, QG, and W-DS made substantial contributions to conception and design, were in charge of data collection, and wrote the manuscript.
clasififacion These were more suitable for clinic and emergency department. Salih et al 7 recently reported that the criteria could be simplified by removing 3 infrequent variables leukopenia, thrombocytopenia, and hypothermiabut could not improve the prediction of mortality and intensive care unit ICU admission. The current findings might have implications for the management of the disease, especially at the emergency department, which may improve survival.
Journal List Medicine Baltimore v. Eur Tubeculosis J ;