Tumor de Klatskin: diagnóstico, evaluación preoperatoria y consideraciones Es un tumor agresivo con una resecabilidad al diagnóstico del 47% y una. Cholangiocarcinomas (CCCs) are malignancies of the biliary duct system Perihilar tumors, also called Klatskin tumors (after Klatskin’s description of them in The etiology of most bile duct cancers remains undetermined. Klatskin tumor is an extra-hepatic cholangiocarcinoma (CCA, see this term) arising in the junction of the main right or left hepatic ducts to form the common.
|Published (Last):||5 February 2015|
|PDF File Size:||19.88 Mb|
|ePub File Size:||18.82 Mb|
|Price:||Free* [*Free Regsitration Required]|
Some authors recommend the use of endoscopically positioned nasobiliary drainage to prevent dissemination at the point of puncture, with a lower incidence of cholangitis and obstruction of the stent than is the case with CPRE. Klatskin tumor is an extra-hepatic cholangiocarcinoma CCA, see canccer term arising in the junction of the main right or left hepatic ducts to form the common hepatic duct.
Hilar Cholangiocarcinoma (Klatskin tumor)
It is characterised by the formation of a tumour mass with clearly defined margins. Due to all of these considerations, surgery is recommended for those patients with unilateral portal involvement or involvement of the confluence in preoperative tests, performing an en-bloc resection cancsr vascular reconstruction. Utility of serum tumor markers as an aid in the differential diagnosis of patients with clinical suspicion of cancer and in patients with cancer of unknown primary site.
Views Read Edit View history. Only 2 years follow-up. Journal of the National Cancer Institute ; Ultrasound, and contrast enhanced helical computerized computed tomography CT can be used in visualizing the extent of disease.
SONOWORLD : Klatskin tumor
Bismuth H, Corlette MB. August Learn how and when to remove this template message. Risk of hepatobiliary and pancreatic cancers after hepatitis C virus infection: Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver. The cause of cholangiocarcinoma has not been defined. Cholangiocarcinoma Klatskin tumor gallbladder: The levels in serum of these markers are strongly influenced by biliary obstruction and jaundice due to their biliary elimination.
National Center for Biotechnology InformationU. Preoperative transcatheter embolization of the portal venous branch for patients receiving extended lobectomy due to the bile duct carcinoma.
Figure 1 Influence of hepatic resection on survival klatskij patients with resected Klatskin tumors from Nakeeb et al Radical en-bloc resection and vascular reconstruction is the technique which has achieved the highest rate of survival in the long term. Of the resected patients, 4 patients 3. It is also the most economical test for preoperative staging. Cholangitis is an uncommon symptom at the time of presentation of cholangiocarcinoma, but frequently occurs after endoscopic or percutaneous biliary tract instrumentation.
Magnetic resonance and magnetic resonance cholangiography RM-cholangiography: Cir Esp, 86pp. In that series, postoperative radiation therapy did not improve survival in either resected or palliated patients. Cholangiography should define not only the location, but also visualize the uppermost extent of the tumor to determine the limits of resectability.
Diagnosis is canxer on clinical and laboratory findings. If preoperative staging suggests unresectable disease, klattskin if the patient is not a suitable surgical candidate, then a nonoperative approach is indicated. It would appear that although hepatectomy increases the probability of negative surgical margin, and therefore a greater chance of cure; an increase in postoperative mortality would kaltskin expected.
Extent of liver resection for hilar cholangiocarcinoma Klatskin tumor: Two-thirds of cases occur in patients over the age of 65, with a near ten-fold increase in patients over 80 years of age. Only comments seeking to improve the quality and accuracy of information on the Orphanet website are accepted.
Patterns and prognostic significance of lymph node dissection for surgical treatment of perihilar and intrahepatic cholangiocarcinoma. Differential diagnosis Autoimmune cholangitis and primary biliary non-Hodgkin’s lymphoma are differential diagnoses of Klatskin tumors. Are you a health professional able to prescribe or dispense drugs?
Another preoperative classification used in the USA is the one published by Jarnagin et al. Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis. Management and treatment Relief of biliary blockage and resection of disease are the main goals of treatment. Papillary phenotype confers improved survival after resection cxncer hilar cholangiocarcinoma.
Major liver resection for carcinoma in jaundiced patients without preoperative biliary drainage. Palliative treatment involves the placement of plastic or metallic biliary stents. Major hepatectomies are safe in patients with cholangiocarcinoma and jaundice.
Squamous cell carcinoma Adenocarcinoma. Surg Gynecol Obstet,pp. Please cite this article as: Efficacy and safety of liver transplantation for patients with cholangiocarcinoma: