Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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The other tests were: Calcium deposits form in the middle layer of the walls of medium-sized vessels, and these vessels become calcified independently of atherosclerosis.

Popliteal artery rupture during total knee replacement in a patient with Monckeberg’s sclerosis. Open in a separate window. National Center for Biotechnology InformationU. It commonly occurs in peripheral arteries of the lower arterioscletosis.

Electromyography plus conduction velocities of the 4 extremities was performed, evidencing a chronic axonal sensorimotor polyneuropathy, denervation with increased amplitude of motor unit action potentials and neuropathic recruitment in distal muscles.

The patient was submitted to exploration of the supragenicular popliteal artery.

Mönckeberg’s sclerosis – is the artery the only target of calcification?

The cause of medial calcinosis remains unclear, but some insights into the etiopathogenic process have been provided by isolated studies.

Acta Diabetol Lat ; Okuno Y, Sato K. N Engl J Med. Although the use of calcium chelators such as sodium thiosulfate has been proposed, the few available studies have monckebrrg to show significant results. Case report A year-old Brazilian woman was referred to the hospital with a year history of an increasing size of the anterior portion of the neck associated with progressive exertional dyspnea, nighttime snoring and coughing, dysphagia of solids and daytime sleepiness.


Medial vascular calcification revisited: Arq Bras Endocrinol Metabol, 52pp.

Monckeberg’s Arteriosclerosis in Uterine Vessels: An Unusual Presentation

J Obstet Gynaecol India. It is frequent to found ulcers of arterial type in the upper and lower limbs of distal predominance, so serious that sometimes may require amputation of the extremity to control the symptoms. Int J Oral Maxillofac Surg, 44pp.

A year-old man with a medical history of stage III nasopharyngeal cancer, end-stage renal disease treated with dialysis, hyperthyroidism, type 2 diabetes mellitus, hypertension, atrial fibrillation, and secondary hyperparathyroidism presented at the Oral Medicine Clinic of the College of Dentistry, University of Florida for dental evaluation prior to the start of radiotherapy.


Find articles by Deeba Kashtwari. Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: Cineangiocoronariography was attempted to directly analyse any coronary disease as a possible cause of these abnormalities, but the rigidity of femoral and brachial arteries impeded the insertion moncekberg the catheter.

Please cite this article as: Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Monckeberg’s sclerosis and atherosclerosis.

Right anterior oblique caudal view showing a normal left main coronary artery. Plain x-ray of both hands posterioanterior view showing calcification in digital arteries A. Macroscopic examination showed stiffened arteries, with extensive plaques and intense parietal calcification process, and the arteries, on palpation, had bone texture.

A phlebolith in the anterior portion of the masseter muscle. At first believed to be a benign condition exclusively involving small-sized and medium-sized arteries, without thrombosis and luminal obstruction characteristic of atherosclerotic disease 4 this condition has now been associated with a multitude zrteriosclerosis systemic conditions, including atherosclerosis, chronic kidney disease and hyperparathyroidism.

Our patient showed no symptoms or arteriosclwrosis of arterial insufficiency, presenting a clinical arteriosclerosus similar to the classical description of Monckeberg’s sclerosis. To the best of our knowledge, this is the first case that has been reported in which this condition presented in the facial vasculature. A review of the problem and a description of a patient with involvement of peripheral, visceral and coronary arteries. Panoramic radiographic identification of carotid arterial plaques.


Mönckeberg’s sclerosis – is the artery the only target of calcification?

One large case series reported intimal aarteriosclerosis on histopathology, 15 a feature strongly inconsistent with the conventional definition of Monckeberg’s sclerosis. Published online Mar Arterioscler Thromb Vasc Biol. Intimal arterial calcification is associated with atherosclerosis, and vascular plaques form within the intima of the involved vessel.

The second theory proposes that the calcification is a consequence of metabolic changes due to necrobiotic lesion of the vessel wall.

Incidentally detected Monckeberg’s sclerosis in a diabetic with coronary artery disease

Report of case and litera Additionally, it worked as a treatment for osteoporosis presented by the patient. Received Apr 25; Accepted Dec A vaginal hysterectomy with pelvic floor repair was done on December 9, So, with the aim of stopping further vascular and soft tissue calcification, intravenous dissodic pamidronate was administred 60 mg IV diluted in mL of saline solution once a day for 1 day.

However, it is likely that a secondary approach will have to be formulated for patients with widespread arterial calcification preventing arterial access altogether. However, the risk of triggering even more tissue calcification secondary to tissue damages discouraged the realization of this procedure.