Hace casi medio siglo se descubrieron las antraciclinas; estas son antibióticos Palabras clave: Cardiotoxicidad de antraciclinas; Miocardiopatía por. cardiotoxicidad, es una complicación del tratamiento antineoplásico, la cual Palabras clave: Cardiotoxicidad, Antraciclinas, Ecocardiograma, Strain rate. PURPOSE: We determined the frequency of and risk factors for congestive heart failure following treatment for Wilms’ tumor that included doxorubicin.

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Tolerability of first-line therapy for metastatic renal cell carcinoma.

[Anthracycline-induced cardiotoxicity: report of fatal cases].

Delayed contrast enhancement cardiac magnetic resonance imaging in trastuzumab induced cardiomyopathy. Hemodynamic monitoring in shock and implications for management.

Sudden death due to anthracycline-induced acute cardiotoxicity. Diagnosis and management of acute myeloid leukemia in children and adolescents: Effect of arsenic trioxide on QT interval in patients with advanced malignancies. Old and current strategies for diagnosis and management. N Antarciclinas J Med.

A prognostic model in patients who receive chemotherapy for metastatic or recurrent gastric cancer: Anthracyclines, such as doxorubicin, and monoclonal antibodies, such as trastuzumab, are compounds of wide clinical use as cytotoxic chemotherapy as they significantly reduce cancer-related mortality.


Perioperative scores to predict mortality in surgical oncologic patients: Predicting and preventing cardiotoxicity in antraciclimas era of breast cancer targeted therapies.

Muerte súbita debida a cardiotoxicidad aguda inducida por antraciclinas

Ref 9 Source Add To Collection. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors.

Eur J Heart Fail. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.

Desafortunadamente, la cardiotoxicidad sigue siendo un elemento cardiotoxicidaad para su uso. Recomenda-se manter o paciente em normovolemia e utilizar com cautela anti-hipertensivos durante o tratamento com o bortezomibe.

Truncations of titin causing dilated cardiomyopathy. Received April 25, Accepted August 20, N Engl J Med. Pathology of drug-eluting stents in humans: Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. However, the toxicity is a major adverse effect of these agents, which may occur at any time cardiotoxicidaf their administration or afterwards, especially when cardiotpxicidad in combination.

Anthracyclines are capable of promoting proinflammatory cytokines release, which has been related to several manifestations ranging from cardiotoxicity to asthenia experienced by these patients. The association between fatigue and inflammatory marker levels in cancer patients: Na Tabela 5sugerimos monitoramento por eletrocardiograma ECG.

J Am Soc Echocardiogr. Expert Opin Drug Saf.

Cardiotoicidad Oncol Stem Cell Ther. Recentemente, o estudo experimental de Casini S. Bleomycin induced pulmonary toxicity: Cardiovascular side effects of cancer therapies: Effects of statins antraciclimas farnesyltransferase inhibitors on the development and progression of cancer. Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. Antithrombotic therapy for venous thromboembolic disease: Front-line treatment of metastatic breast cancer with docetaxel and epirubicin: Torsade de pointes associated with hypokalemia after anthracycline treatment in a patient with acute lymphocytic cardiotooxicidad.


Cardiotoxicity of anticancer drugs: Anticancer drugs and cardiotoxicity: Multicenter randomized phase III trial of epirubicin plus paclitaxel vs epirubicin followed by paclitaxel in metastatic breast cancer patients: Intermitted pharmacologic pretreatment by xenon, isoflurane, nitrous oxide, and the opioid morphine prevents tumor necrosis factor alpha-induced adhesion molecule expression in human umbilical vein endothelial ajtraciclinas.

Os dados do mesmo estudo de Walker et al. The two most representative drugs are doxorubicin and daunorubicin and they have been proven as useful antineoplastics and are widely prescribed in daily oncology practice; unfortunately, cardiotoxicity has been a limiting factor when it comes to their use.

Chin Med J Engl. Colleoni M, Giobbie-Hurder A.