Results 1 – 8 Download Chimico farmaceutica savelli bruno and more books of the same author and others for free. a) F. SAVELLI, O. BRUNO: Analisi chimico Farmaceutica – Editore c) G.C. PORRETTA: Analisi quantitativa di composti farmaceutici – CISU. 5 a Ed. ETS Editrice, Pisa F. Savelli, O. Bruno. Analisi Chimico Farmaceutica – Piccin, Padova, A. Carta, M. G. Mamolo, F. Novelli.

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The student who successfully completes the course will be able to demonstrate a solid knowledge of the main methodologies involved in an analytical process aimed at identifying the identity and the purity of unknown compounds and, in particular, of compounds included in the European Pharmacopoeia. Selectivity toward different isozymes and receptor anlaisi. Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche. SID – Sistema informatico dipartimentale Direzione servizi informatici e amministrazione digitale Direzione Edilizia e Telecomunicazione.


Direct analysis of a strong and a weak acid solution with conductimeter. Riconoscimento di sostanze organiche e di farmaci metallo-organici e organici inclusi nella Farmacopea Europea.


Direct and indirect conductimetry. ETS Editrice, Pisa Individuazione dell’azoto, zolfo, alogeni, fosforo, arsenico. The drug discovery process. Laboratory class for in total 24 hours, divided into 6 sessions. Lipophilicity definitions and lipophilicity scales. Assessment criteria of skills.

Salta alla navigazione Strumenti personali. Interaction of drugs with receptors full, partial or inverse agonists, antagonistsenzymes reversible, irreversible, allosteric inhibitors and other biological targets.

Didactic methods Lectures for in total 32 hours: Identificazione sistematica di composti organici – Editoriale Grasso, Bologna, Vogel’s textbook of practical organic chemistry – 5th Ed. Basic operations in organic chemistry laboratory. Dipartimento di Scienze della Vita e Biotecnologie Coordinatore: Stadi per l’identificazione di un composto organico. General Medicinal Chemistry part.

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Physicochemical properties of drugs and relation between biological ADME behavior and structural features. Varmaceutica dei componenti di una miscela; esame organolettico; determinazione della purezza di un campione. Manuale di chimica farmaceutica.

Initially the students will be trained to understand the general nature of their analytes organic, inorganic, mixed. Electrical conductivity of solutions and laws of conductivity.

Sostanze organiche, inorganiche, a composizione mista; sostanze pure, impure, in miscela; comportamento delle Sostanze al calore. Stoichiometric calculations, mass and volume measurements. Estrazione con solventi; sublimazione; distillazione semplice e frazionata; rettifica; miscele azeotropiche; distillazione in corrente di vapore; distillazione a pressione ridotta.


The work in the exercitation is done either individually or in pairs, depending on its difficulty. Prodrugs and bioprecursors strategy. Lead compound optimisation, candidate compound selection, pharmacophore. Gruppi funzionali e reazioni di riconoscimento. Natura di un campione analitico.

Fundamental operations and general equipment in a chemical laboratory. Then they will proceed with a qualitative analysis of the sample by determining its elemental composition, solubility, functional groups and the most relevant physical constants. How drugs bind with their target, polar and non-polar binding interactions.

Target identification and validation, lead identification. Main metabolic phases chimcio and 2 transformations. Conductivity cells and conductimeter. Assessment criteria of behaviors. Vogel’s textbook of practical asvelli chemistry – 5th Ed.

Strategy and tactics in drug discovery.